What is the molecular formula of semaglutide?
Semaglutide has the molecular formula C187H291N45O59. The corresponding molecular weight is 4114.0 g/mol. CAS Registry Number 910463-68-2. PubChem CID 56843331. Synonyms include GLP-1 analogue with C18 fatty diacid side chain. The expected mass for identity confirmation by mass spectrometry is derived from this formula.
Formula. C187H291N45O59.
Analytical note. The expected mass for identity confirmation by mass spectrometry is derived from this formula. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use.
Sources
Semaglutide: reference facts
7 Semaglutide values, each linked to its public source; see the Semaglutide reference page.
| Synonyms | GLP-1 analogue with C18 fatty diacid side chain (pubchem.ncbi.nlm.nih.gov) |
|---|---|
| Compound class | peptide (lipidated) (pubchem.ncbi.nlm.nih.gov) |
| CAS Registry Number | 910463-68-2 (pubchem.ncbi.nlm.nih.gov) |
| Molecular formula | C187H291N45O59 (pubchem.ncbi.nlm.nih.gov) |
| Molecular weight | 4114.0 g/mol (pubchem.ncbi.nlm.nih.gov) |
| PubChem CID | 56843331 (pubchem.ncbi.nlm.nih.gov) |
| Storage (lyophilised) | -20 °C, dry, protected from light (sigmaaldrich.com) |
Sizes and prices at Sable
| Vial | Price | Per mg | UK same-size check (2026-10-16) |
|---|---|---|---|
| 1 mg | £21.49 | £21.49 | no same-size match |
| 2 mg | £34.99 | £17.50 | no same-size match |
| 5 mg | £28.98 | £5.80 | no same-size match |
| 8 mg | £66.49 | £8.31 | no same-size match |
| 10 mg | £38.98 | £3.90 | no same-size match |
| 20 mg | £64.98 | £3.25 | no same-size match |
| 30 mg | £84.98 | £2.83 | no same-size match |
Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: CoA library.
Typical analytical method
| HPLC column | C18 reversed-phase (300 A pore, C4/C8 suitable for large/lipidated) |
|---|---|
| Mobile phase | A: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min) |
| Detection | 214-220 nm (peptide bond) |
General literature method. The lot CoA records the method actually used. How to read an HPLC chromatogram.
Related questions
Lyophilised storage on file: Semaglutide
From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See peptide storage.
| Compound | Lyophilised storage | Light / notes |
|---|---|---|
| Semaglutide | -20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeks | protect from light; no specific sequence liabilities identified from sequence data on file (source) |
Typical analytical method: Semaglutide
Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See how to read a CoA.
| Compound | HPLC column / detection | MS / expected ion |
|---|---|---|
| Semaglutide | C18 reversed-phase (300 A pore, C4/C8 suitable for large/lipidated); 214-220 nm (peptide bond) | ESI-MS (positive mode); LC-MS for identity; [M+3H]3+ ~1372.3; [M+4H]4+ ~1029.5; [M+5H]5+ ~823.8; [M+6H]6+ ~686.7 |
Research use only. Not a medicine. Not for human or veterinary use.