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What is the molecular weight of cagrilintide?

The molecular weight of Cagrilintide is 4409.0 g/mol on the registry record used for identity. The molecular formula is C194H312N54O59S2. CAS Registry Number 1415456-99-3. PubChem CID 171397054. It is classed as a peptide (lipidated). Synonyms include long-acting acylated amylin analogue.

Mass. The expected average mass for identity confirmation is 4409.0 g/mol.

Formula. C194H312N54O59S2.

Analytical note. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use.

Sources

Cagrilintide: reference facts

7 Cagrilintide values, each linked to its public source; see the Cagrilintide reference page.

Synonymslong-acting acylated amylin analogue (pubchem.ncbi.nlm.nih.gov)
Compound classpeptide (lipidated) (pubchem.ncbi.nlm.nih.gov)
CAS Registry Number1415456-99-3 (pubchem.ncbi.nlm.nih.gov)
Molecular formulaC194H312N54O59S2 (pubchem.ncbi.nlm.nih.gov)
Molecular weight4409.0 g/mol (pubchem.ncbi.nlm.nih.gov)
PubChem CID171397054 (pubchem.ncbi.nlm.nih.gov)
Storage (lyophilised)-20 °C, dry, protected from light (sigmaaldrich.com)

Sizes and prices at Sable

VialPricePer mgUK same-size check (2026-10-16)
2 mg£25.99£13.00no same-size match
5 mg£28.98£5.80lowest other £29.00 across 1 UK sellers
10 mg£43.99£4.40lowest other £65.00 across 2 UK sellers

Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: CoA library.

Typical analytical method

HPLC columnC18 reversed-phase (300 A pore, C4/C8 suitable for large/lipidated)
Mobile phaseA: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min)
Detection214-220 nm (peptide bond)

General literature method. The lot CoA records the method actually used. How to read an HPLC chromatogram.

Related questions

Lyophilised storage on file: Cagrilintide

From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See peptide storage.

CompoundLyophilised storageLight / notes
Cagrilintide-20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeksprotect from light; contains Met/Cys/Trp: oxidation-prone; minimise air/headspace exposure (source)

Typical analytical method: Cagrilintide

Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See how to read a CoA.

CompoundHPLC column / detectionMS / expected ion
CagrilintideC18 reversed-phase (300 A pore, C4/C8 suitable for large/lipidated); 214-220 nm (peptide bond)ESI-MS (positive mode); LC-MS for identity; [M+3H]3+ ~1470.7; [M+4H]4+ ~1103.3; [M+5H]5+ ~882.8; [M+6H]6+ ~735.8

Research use only. Not a medicine. Not for human or veterinary use.