Glossary

Diisopropylcarbodiimide

N,N'-Diisopropylcarbodiimide (DIC) is a carbodiimide coupling reagent used in peptide synthesis. Unlike DCC, its urea by-product is soluble in common solvents, which suits solid-phase methods. DIC is typically used with additives such as Oxyma Pure or HOBt to increase efficiency and suppress racemisation.

Source: en.wikipedia.org

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