Glossary

Deamidation

Deamidation is a chemical reaction in which the side-chain amide of asparagine or glutamine is removed, converting it to aspartic acid, isoaspartic acid or glutamic acid. It increases mass by about 0.98 Da and introduces a negative charge. Deamidation is accelerated at neutral to alkaline pH and elevated temperature, especially at Asn-Gly sequences.

Source: en.wikipedia.org

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