Glossary
D-amino acid
A D-amino acid is the mirror-image form (enantiomer) of the more common L-amino acid. Substituting D-residues into a peptide can change its three-dimensional structure and makes it much less recognisable to most proteases, increasing stability in biological matrices. Retro-inverso peptides use D-amino acids in reversed sequence order to mimic side-chain topology of the parent.
Source: en.wikipedia.org
Related terms
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