What is the amino acid sequence of thymosin alpha-1?
Thymosin alpha-1 is a research peptide whose amino acid sequence is on the public registry record. The published sequence is Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN. Its molecular formula is C129H215N33O55. Its molecular weight is 3108.3 g/mol. The CAS Registry Number is 62304-98-7. PubChem CID 16130571 indexes the structure.
Sequence. Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN
Class. peptide.
Formula. C129H215N33O55.
Mass. 3108.3 g/mol.
Analytical note. Identity confirmation by mass spectrometry uses the mass calculated from the formula. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use.
Sources
Thymosin alpha-1: reference facts
8 Thymosin alpha-1 values, each linked to its public source; see the Thymosin alpha-1 reference page.
| Synonyms | thymalfasin; Ta1 (pubchem.ncbi.nlm.nih.gov) |
|---|---|
| Compound class | peptide (pubchem.ncbi.nlm.nih.gov) |
| CAS Registry Number | 62304-98-7 (pubchem.ncbi.nlm.nih.gov) |
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN (pubchem.ncbi.nlm.nih.gov) |
| Molecular formula | C129H215N33O55 (pubchem.ncbi.nlm.nih.gov) |
| Molecular weight | 3108.3 g/mol (pubchem.ncbi.nlm.nih.gov) |
| PubChem CID | 16130571 (pubchem.ncbi.nlm.nih.gov) |
| Storage (lyophilised) | -20 °C, dry, protected from light (sigmaaldrich.com) |
Calculated sequence properties
Computed from the listed sequence. See the methodology.
| Length | 28 residues |
|---|---|
| Theoretical pI | 3.81 (calculated from sequence) |
| Net charge at pH 7 | -5.99 (calculated) |
Sizes and prices at Sable
| Vial | Price | Per mg | UK same-size check (2026-10-16) |
|---|---|---|---|
| 5 mg | £17.93 | £3.59 | lowest other £17.95 across 6 UK sellers |
| 10 mg | £27.98 | £2.80 | lowest other £28.00 across 5 UK sellers |
Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: CoA library.
Typical analytical method
| HPLC column | C18 reversed-phase (100-120 A pore) |
|---|---|
| Mobile phase | A: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min) |
| Detection | 214-220 nm (peptide bond) |
General literature method. The lot CoA records the method actually used. How to read an HPLC chromatogram.
Related questions
Lyophilised storage on file: Thymosin alpha-1
From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See peptide storage.
| Compound | Lyophilised storage | Light / notes |
|---|---|---|
| Thymosin alpha-1 | -20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeks | protect from light; no specific sequence liabilities identified from sequence data on file (source) |
Typical analytical method: Thymosin alpha-1
Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See how to read a CoA.
| Compound | HPLC column / detection | MS / expected ion |
|---|---|---|
| Thymosin alpha-1 | C18 reversed-phase (100-120 A pore); 214-220 nm (peptide bond) | ESI-MS (positive mode); LC-MS for identity; [M+3H]3+ ~1037.1; [M+4H]4+ ~778.1; [M+5H]5+ ~622.7; [M+6H]6+ ~519.1 |
Research use only. Not a medicine. Not for human or veterinary use.