What is the amino acid sequence of TB-500?
TB-500 is a research peptide whose amino acid sequence is on the public registry record. The published sequence is Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln. Its molecular formula is C38H68N10O14. Its molecular weight is 889.0 g/mol. The CAS Registry Number is 885340-08-9. PubChem CID 62707662 indexes the structure.
Sequence. Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
Class. peptide.
Formula. C38H68N10O14.
Mass. 889.0 g/mol.
Analytical note. Identity confirmation by mass spectrometry uses the mass calculated from the formula. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use.
Sources
TB-500: reference facts
8 TB-500 values, each linked to its public source; see the TB-500 reference page.
| Synonyms | synthetic thymosin beta-4 fragment (Ac-LKKTETQ) (pubchem.ncbi.nlm.nih.gov) |
|---|---|
| Compound class | peptide (pubchem.ncbi.nlm.nih.gov) |
| CAS Registry Number | 885340-08-9 (pubchem.ncbi.nlm.nih.gov) |
| Sequence | Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln (pubchem.ncbi.nlm.nih.gov) |
| Molecular formula | C38H68N10O14 (pubchem.ncbi.nlm.nih.gov) |
| Molecular weight | 889.0 g/mol (pubchem.ncbi.nlm.nih.gov) |
| PubChem CID | 62707662 (pubchem.ncbi.nlm.nih.gov) |
| Storage (lyophilised) | -20 °C, dry, protected from light (sigmaaldrich.com) |
Calculated sequence properties
Computed from the listed sequence. See the methodology.
| Length | 7 residues |
|---|---|
| Theoretical pI | 7.36 (calculated from sequence) |
| Net charge at pH 7 | 0 (calculated) |
Sizes and prices at Sable
| Vial | Price | Per mg | UK same-size check (2026-10-16) |
|---|---|---|---|
| 2 mg | £14.26 | £7.13 | lowest other £14.95 across 4 UK sellers |
| 5 mg | £13.93 | £2.79 | lowest other £13.95 across 15 UK sellers |
| 10 mg | £10.99 | £1.10 | lowest other £22.95 across 14 UK sellers |
| 15 mg | £57.49 | £3.83 | no same-size match |
| 20 mg | £39.98 | £2.00 | lowest other £40.00 across 1 UK sellers |
Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: CoA library.
Typical analytical method
| HPLC column | C18 reversed-phase (100-120 A pore) |
|---|---|
| Mobile phase | A: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min) |
| Detection | 214-220 nm (peptide bond) |
General literature method. The lot CoA records the method actually used. How to read an HPLC chromatogram.
Related questions
Lyophilised storage on file: TB-500
From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See peptide storage.
| Compound | Lyophilised storage | Light / notes |
|---|---|---|
| TB-500 | -20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeks | protect from light; no specific sequence liabilities identified from sequence data on file (source) |
Typical analytical method: TB-500
Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See how to read a CoA.
| Compound | HPLC column / detection | MS / expected ion |
|---|---|---|
| TB-500 | C18 reversed-phase (100-120 A pore); 214-220 nm (peptide bond) | ESI-MS (positive mode); LC-MS for identity; [M+1H]1+ ~890.0; [M+2H]2+ ~445.5; [M+3H]3+ ~297.3 |
Research use only. Not a medicine. Not for human or veterinary use.