What is the amino acid sequence of Semax?
Semax is a research peptide whose amino acid sequence is on the public registry record. The published sequence is Met-Glu-His-Phe-Pro-Gly-Pro. Its molecular formula is C37H51N9O10S. Its molecular weight is 813.9 g/mol. The CAS Registry Number is 80714-61-0. PubChem CID 9811102 indexes the structure.
Sequence. Met-Glu-His-Phe-Pro-Gly-Pro
Class. peptide.
Formula. C37H51N9O10S.
Mass. 813.9 g/mol.
Analytical note. Identity confirmation by mass spectrometry uses the mass calculated from the formula. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use.
Sources
Semax: reference facts
8 Semax values, each linked to its public source; see the Semax reference page.
| Synonyms | ACTH (4-7) Pro-Gly-Pro; Met-Glu-His-Phe-Pro-Gly-Pro (pubchem.ncbi.nlm.nih.gov) |
|---|---|
| Compound class | peptide (pubchem.ncbi.nlm.nih.gov) |
| CAS Registry Number | 80714-61-0 (pubchem.ncbi.nlm.nih.gov) |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro (pubchem.ncbi.nlm.nih.gov) |
| Molecular formula | C37H51N9O10S (pubchem.ncbi.nlm.nih.gov) |
| Molecular weight | 813.9 g/mol (pubchem.ncbi.nlm.nih.gov) |
| PubChem CID | 9811102 (pubchem.ncbi.nlm.nih.gov) |
| Storage (lyophilised) | -20 °C, dry, protected from light (sigmaaldrich.com) |
Calculated sequence properties
Computed from the listed sequence. See the methodology.
| Length | 7 residues |
|---|---|
| Theoretical pI | 5.36 (calculated from sequence) |
| Net charge at pH 7 | -0.78 (calculated) |
Sizes and prices at Sable
| Vial | Price | Per mg | UK same-size check (2026-10-16) |
|---|---|---|---|
| 5 mg | £13.99 | £2.80 | lowest other £15.95 across 8 UK sellers |
| 10 mg | £15.93 | £1.59 | lowest other £15.95 across 10 UK sellers |
| 30 mg | £24.98 | £0.83 | lowest other £45.00 across 1 UK sellers |
Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: CoA library.
Typical analytical method
| HPLC column | C18 reversed-phase (100-120 A pore) |
|---|---|
| Mobile phase | A: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min) |
| Detection | 214-220 nm (peptide bond) |
General literature method. The lot CoA records the method actually used. How to read an HPLC chromatogram.
Related questions
Lyophilised storage on file: Semax
From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See peptide storage.
| Compound | Lyophilised storage | Light / notes |
|---|---|---|
| Semax | -20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeks | protect from light; contains Met/Cys/Trp: oxidation-prone; minimise air/headspace exposure (source) |
Typical analytical method: Semax
Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See how to read a CoA.
| Compound | HPLC column / detection | MS / expected ion |
|---|---|---|
| Semax | C18 reversed-phase (100-120 A pore); 214-220 nm (peptide bond) | ESI-MS (positive mode); LC-MS for identity; [M+1H]1+ ~814.9; [M+2H]2+ ~408.0; [M+3H]3+ ~272.3 |
Research use only. Not a medicine. Not for human or veterinary use.