Sable · Question
What is the difference between MOTS-c and Tirzepatide?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
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Last verified 2026-10-10
What is the difference between MOTS-c and Tirzepatide?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
Which is heavier, MOTS-c or Tirzepatide?
MOTS-c has a molecular weight of about 2174.6 g/mol and Tirzepatide about 4813 g/mol (PubChem), so Tirzepatide is heavier by 2,638.4 g/mol, a ratio of 2.21. This means 1 mg of MOTS-c contains 459.9 nmol versus 207.8 nmol for Tirzepatide.
How many mg of Tirzepatide are equimolar to 1 mg of MOTS-c?
1 mg of MOTS-c (MW 2174.6) is 459.9 nmol. The same number of moles of Tirzepatide (MW 4813) weighs 2.213 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of MOTS-c and Tirzepatide
PubChem lists MOTS-c as C101H152N28O22S2 (2174.6 g/mol) and Tirzepatide as C225H348N48O68 (4813 g/mol). MOTS-c is a peptide; Tirzepatide is a peptide (lipidated). These formulas refer to the parent compounds without salt counter-ions.
A 5 mg vial of MOTS-c equals how many mg of Tirzepatide in moles?
5 mg of MOTS-c (MW 2174.6) is 2.299 µmol. The same amount of Tirzepatide (MW 4813) would weigh 11.066 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of MOTS-c equals how many mg of Tirzepatide in moles?
10 mg of MOTS-c (MW 2174.6) is 4.599 µmol. The same amount of Tirzepatide (MW 4813) would weigh 22.133 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of MOTS-c equals how many mg of Tirzepatide in moles?
20 mg of MOTS-c (MW 2174.6) is 9.197 µmol. The same amount of Tirzepatide (MW 4813) would weigh 44.266 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 30 mg vial of MOTS-c equals how many mg of Tirzepatide in moles?
30 mg of MOTS-c (MW 2174.6) is 13.796 µmol. The same amount of Tirzepatide (MW 4813) would weigh 66.398 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 40 mg vial of MOTS-c equals how many mg of Tirzepatide in moles?
40 mg of MOTS-c (MW 2174.6) is 18.394 µmol. The same amount of Tirzepatide (MW 4813) would weigh 88.531 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of Tirzepatide equals how many mg of MOTS-c in moles?
20 mg of Tirzepatide (MW 4813) is 4.155 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 9.036 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of Tirzepatide equals how many mg of MOTS-c in moles?
10 mg of Tirzepatide (MW 4813) is 2.078 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 4.518 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of Tirzepatide equals how many mg of MOTS-c in moles?
5 mg of Tirzepatide (MW 4813) is 1.039 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 2.259 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 30 mg vial of Tirzepatide equals how many mg of MOTS-c in moles?
30 mg of Tirzepatide (MW 4813) is 6.233 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 13.555 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 40 mg vial of Tirzepatide equals how many mg of MOTS-c in moles?
40 mg of Tirzepatide (MW 4813) is 8.311 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 18.073 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 15 mg vial of Tirzepatide equals how many mg of MOTS-c in moles?
15 mg of Tirzepatide (MW 4813) is 3.117 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 6.777 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 60 mg vial of Tirzepatide equals how many mg of MOTS-c in moles?
60 mg of Tirzepatide (MW 4813) is 12.466 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 27.109 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between MOTS-c and Tirzepatide?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-tirzepatide/#sqa-040013
APA
Sable Peptides. (2026, October 11). *What is the difference between MOTS-c and Tirzepatide?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-tirzepatide/#sqa-040013
BibTeX
@misc{sable_#sqa-040013_2026,
author = {{Sable Peptides}},
title = {{What is the difference between MOTS-c and Tirzepatide?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-tirzepatide/#sqa-040013}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10