Sable · Question
What is the difference between MOTS-c and TB-500?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
Research use only. Not for human consumption. No health claims.
Last verified 2026-10-10
What is the difference between MOTS-c and TB-500?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
Which is heavier, MOTS-c or TB-500?
MOTS-c has a molecular weight of about 2174.6 g/mol and TB-500 about 889 g/mol (PubChem), so MOTS-c is heavier by 1,285.6 g/mol, a ratio of 2.45. This means 1 mg of MOTS-c contains 459.9 nmol versus 1,124.9 nmol for TB-500.
How many mg of TB-500 are equimolar to 1 mg of MOTS-c?
1 mg of MOTS-c (MW 2174.6) is 459.9 nmol. The same number of moles of TB-500 (MW 889) weighs 0.4088 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of MOTS-c and TB-500
PubChem lists MOTS-c as C101H152N28O22S2 (2174.6 g/mol) and TB-500 as C38H68N10O14 (889 g/mol). MOTS-c is a peptide; TB-500 is a peptide. These formulas refer to the parent compounds without salt counter-ions.
A 5 mg vial of MOTS-c equals how many mg of TB-500 in moles?
5 mg of MOTS-c (MW 2174.6) is 2.299 µmol. The same amount of TB-500 (MW 889) would weigh 2.044 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of MOTS-c equals how many mg of TB-500 in moles?
10 mg of MOTS-c (MW 2174.6) is 4.599 µmol. The same amount of TB-500 (MW 889) would weigh 4.088 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of MOTS-c equals how many mg of TB-500 in moles?
20 mg of MOTS-c (MW 2174.6) is 9.197 µmol. The same amount of TB-500 (MW 889) would weigh 8.176 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 30 mg vial of MOTS-c equals how many mg of TB-500 in moles?
30 mg of MOTS-c (MW 2174.6) is 13.796 µmol. The same amount of TB-500 (MW 889) would weigh 12.264 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 40 mg vial of MOTS-c equals how many mg of TB-500 in moles?
40 mg of MOTS-c (MW 2174.6) is 18.394 µmol. The same amount of TB-500 (MW 889) would weigh 16.352 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of TB-500 equals how many mg of MOTS-c in moles?
10 mg of TB-500 (MW 889) is 11.249 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 24.461 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 2 mg vial of TB-500 equals how many mg of MOTS-c in moles?
2 mg of TB-500 (MW 889) is 2.25 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 4.892 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of TB-500 equals how many mg of MOTS-c in moles?
5 mg of TB-500 (MW 889) is 5.624 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 12.231 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 15 mg vial of TB-500 equals how many mg of MOTS-c in moles?
15 mg of TB-500 (MW 889) is 16.873 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 36.692 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of TB-500 equals how many mg of MOTS-c in moles?
20 mg of TB-500 (MW 889) is 22.497 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 48.922 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between MOTS-c and TB-500?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-tb-500/#sqa-040053
APA
Sable Peptides. (2026, October 11). *What is the difference between MOTS-c and TB-500?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-tb-500/#sqa-040053
BibTeX
@misc{sable_#sqa-040053_2026,
author = {{Sable Peptides}},
title = {{What is the difference between MOTS-c and TB-500?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-tb-500/#sqa-040053}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10