Sable · Question
What is the difference between MOTS-c and SS-31?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
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Last verified 2026-10-10
What is the difference between MOTS-c and SS-31?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
Which is heavier, MOTS-c or SS-31?
MOTS-c has a molecular weight of about 2174.6 g/mol and SS-31 about 639.8 g/mol (PubChem), so MOTS-c is heavier by 1,534.8 g/mol, a ratio of 3.4. This means 1 mg of MOTS-c contains 459.9 nmol versus 1,563 nmol for SS-31.
How many mg of SS-31 are equimolar to 1 mg of MOTS-c?
1 mg of MOTS-c (MW 2174.6) is 459.9 nmol. The same number of moles of SS-31 (MW 639.8) weighs 0.2942 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of MOTS-c and SS-31
PubChem lists MOTS-c as C101H152N28O22S2 (2174.6 g/mol) and SS-31 as C32H49N9O5 (639.8 g/mol). MOTS-c is a peptide; SS-31 is a peptide. These formulas refer to the parent compounds without salt counter-ions.
A 5 mg vial of MOTS-c equals how many mg of SS-31 in moles?
5 mg of MOTS-c (MW 2174.6) is 2.299 µmol. The same amount of SS-31 (MW 639.8) would weigh 1.471 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of MOTS-c equals how many mg of SS-31 in moles?
10 mg of MOTS-c (MW 2174.6) is 4.599 µmol. The same amount of SS-31 (MW 639.8) would weigh 2.942 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of MOTS-c equals how many mg of SS-31 in moles?
20 mg of MOTS-c (MW 2174.6) is 9.197 µmol. The same amount of SS-31 (MW 639.8) would weigh 5.884 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 30 mg vial of MOTS-c equals how many mg of SS-31 in moles?
30 mg of MOTS-c (MW 2174.6) is 13.796 µmol. The same amount of SS-31 (MW 639.8) would weigh 8.826 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 40 mg vial of MOTS-c equals how many mg of SS-31 in moles?
40 mg of MOTS-c (MW 2174.6) is 18.394 µmol. The same amount of SS-31 (MW 639.8) would weigh 11.769 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of SS-31 equals how many mg of MOTS-c in moles?
5 mg of SS-31 (MW 639.8) is 7.815 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 16.994 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of SS-31 equals how many mg of MOTS-c in moles?
10 mg of SS-31 (MW 639.8) is 15.63 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 33.989 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between MOTS-c and SS-31?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-ss-31/#sqa-039985
APA
Sable Peptides. (2026, October 11). *What is the difference between MOTS-c and SS-31?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-ss-31/#sqa-039985
BibTeX
@misc{sable_#sqa-039985_2026,
author = {{Sable Peptides}},
title = {{What is the difference between MOTS-c and SS-31?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-ss-31/#sqa-039985}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10