Sable · Question
What is the difference between MOTS-c and PT-141?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
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Last verified 2026-10-10
What is the difference between MOTS-c and PT-141?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
Which is heavier, MOTS-c or PT-141?
MOTS-c has a molecular weight of about 2174.6 g/mol and PT-141 about 1025.2 g/mol (PubChem), so MOTS-c is heavier by 1,149.4 g/mol, a ratio of 2.12. This means 1 mg of MOTS-c contains 459.9 nmol versus 975.4 nmol for PT-141.
How many mg of PT-141 are equimolar to 1 mg of MOTS-c?
1 mg of MOTS-c (MW 2174.6) is 459.9 nmol. The same number of moles of PT-141 (MW 1025.2) weighs 0.4714 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of MOTS-c and PT-141
PubChem lists MOTS-c as C101H152N28O22S2 (2174.6 g/mol) and PT-141 as C50H68N14O10 (1025.2 g/mol). MOTS-c is a peptide; PT-141 is a cyclic peptide. These formulas refer to the parent compounds without salt counter-ions.
A 5 mg vial of MOTS-c equals how many mg of PT-141 in moles?
5 mg of MOTS-c (MW 2174.6) is 2.299 µmol. The same amount of PT-141 (MW 1025.2) would weigh 2.357 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of MOTS-c equals how many mg of PT-141 in moles?
10 mg of MOTS-c (MW 2174.6) is 4.599 µmol. The same amount of PT-141 (MW 1025.2) would weigh 4.714 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of MOTS-c equals how many mg of PT-141 in moles?
20 mg of MOTS-c (MW 2174.6) is 9.197 µmol. The same amount of PT-141 (MW 1025.2) would weigh 9.429 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 30 mg vial of MOTS-c equals how many mg of PT-141 in moles?
30 mg of MOTS-c (MW 2174.6) is 13.796 µmol. The same amount of PT-141 (MW 1025.2) would weigh 14.143 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 40 mg vial of MOTS-c equals how many mg of PT-141 in moles?
40 mg of MOTS-c (MW 2174.6) is 18.394 µmol. The same amount of PT-141 (MW 1025.2) would weigh 18.858 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of PT-141 equals how many mg of MOTS-c in moles?
10 mg of PT-141 (MW 1025.2) is 9.754 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 21.211 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of PT-141 equals how many mg of MOTS-c in moles?
5 mg of PT-141 (MW 1025.2) is 4.877 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 10.606 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between MOTS-c and PT-141?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-pt-141/#sqa-039977
APA
Sable Peptides. (2026, October 11). *What is the difference between MOTS-c and PT-141?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-pt-141/#sqa-039977
BibTeX
@misc{sable_#sqa-039977_2026,
author = {{Sable Peptides}},
title = {{What is the difference between MOTS-c and PT-141?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/mots-c-vs-pt-141/#sqa-039977}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10