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What is the difference between Melanotan I and Semaglutide?

Melanotan I is a linear 13-residue alpha-MSH analogue used in melanocortin-1 receptor research (peptide, MW about 1646.8 g/mol).

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Last verified 2026-10-10

What is the difference between Melanotan I and Semaglutide?

Melanotan I is a linear 13-residue alpha-MSH analogue used in melanocortin-1 receptor research (peptide, MW about 1646.8 g/mol).

Which is heavier, Melanotan I or Semaglutide?

Melanotan I has a molecular weight of about 1646.8 g/mol and Semaglutide about 4114 g/mol (PubChem), so Semaglutide is heavier by 2,467.2 g/mol, a ratio of 2.5. This means 1 mg of Melanotan I contains 607.2 nmol versus 243.1 nmol for Semaglutide.

How many mg of Semaglutide are equimolar to 1 mg of Melanotan I?

1 mg of Melanotan I (MW 1646.8) is 607.2 nmol. The same number of moles of Semaglutide (MW 4114) weighs 2.498 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.

Compare the molecular formulas of Melanotan I and Semaglutide

PubChem lists Melanotan I as C78H111N21O19 (1646.8 g/mol) and Semaglutide as C187H291N45O59 (4114 g/mol). Melanotan I is a peptide; Semaglutide is a peptide (lipidated). These formulas refer to the parent compounds without salt counter-ions.

A 5 mg vial of Melanotan I equals how many mg of Semaglutide in moles?

5 mg of Melanotan I (MW 1646.8) is 3.036 µmol. The same amount of Semaglutide (MW 4114) would weigh 12.491 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 10 mg vial of Melanotan I equals how many mg of Semaglutide in moles?

10 mg of Melanotan I (MW 1646.8) is 6.072 µmol. The same amount of Semaglutide (MW 4114) would weigh 24.982 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 1 mg vial of Semaglutide equals how many mg of Melanotan I in moles?

1 mg of Semaglutide (MW 4114) is 0.2431 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 0.4003 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 2 mg vial of Semaglutide equals how many mg of Melanotan I in moles?

2 mg of Semaglutide (MW 4114) is 0.4861 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 0.8006 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 8 mg vial of Semaglutide equals how many mg of Melanotan I in moles?

8 mg of Semaglutide (MW 4114) is 1.945 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 3.202 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 5 mg vial of Semaglutide equals how many mg of Melanotan I in moles?

5 mg of Semaglutide (MW 4114) is 1.215 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 2.001 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 10 mg vial of Semaglutide equals how many mg of Melanotan I in moles?

10 mg of Semaglutide (MW 4114) is 2.431 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 4.003 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 20 mg vial of Semaglutide equals how many mg of Melanotan I in moles?

20 mg of Semaglutide (MW 4114) is 4.861 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 8.006 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 30 mg vial of Semaglutide equals how many mg of Melanotan I in moles?

30 mg of Semaglutide (MW 4114) is 7.292 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 12.009 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

More questions about melanotan-i

A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.

Cite this

Research use only. Not for consumption. No health claims.

Plain

Sable Peptides. (2026). What is the difference between Melanotan I and Semaglutide?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/melanotan-i-vs-semaglutide/#sqa-040092

APA

Sable Peptides. (2026, October 11). *What is the difference between Melanotan I and Semaglutide?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/melanotan-i-vs-semaglutide/#sqa-040092

BibTeX

@misc{sable_#sqa-040092_2026,
  author = {{Sable Peptides}},
  title = {{What is the difference between Melanotan I and Semaglutide?}},
  year = {2026},
  howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/melanotan-i-vs-semaglutide/#sqa-040092}},
  note = {Accessed 11 October 2026. CC BY 4.0}
}

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Date modified: 2026-10-10