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What is the difference between Melanotan I and Pal-GHK?

Melanotan I is a linear 13-residue alpha-MSH analogue used in melanocortin-1 receptor research (peptide, MW about 1646.8 g/mol). Pal-GHK is a palmitoylated form of the GHK tripeptide used in cosmetic-science and fibroblast-culture research (lipopeptide, MW about 578.8 g/mol).

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Last verified 2026-10-10

What is the difference between Melanotan I and Pal-GHK?

Melanotan I is a linear 13-residue alpha-MSH analogue used in melanocortin-1 receptor research (peptide, MW about 1646.8 g/mol). Pal-GHK is a palmitoylated form of the GHK tripeptide used in cosmetic-science and fibroblast-culture research (lipopeptide, MW about 578.8 g/mol).

Which is heavier, Melanotan I or Pal-GHK?

Melanotan I has a molecular weight of about 1646.8 g/mol and Pal-GHK about 578.8 g/mol (PubChem), so Melanotan I is heavier by 1,068 g/mol, a ratio of 2.85. This means 1 mg of Melanotan I contains 607.2 nmol versus 1,727.7 nmol for Pal-GHK.

How many mg of Pal-GHK are equimolar to 1 mg of Melanotan I?

1 mg of Melanotan I (MW 1646.8) is 607.2 nmol. The same number of moles of Pal-GHK (MW 578.8) weighs 0.3515 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.

Compare the molecular formulas of Melanotan I and Pal-GHK

PubChem lists Melanotan I as C78H111N21O19 (1646.8 g/mol) and Pal-GHK as C30H54N6O5 (578.8 g/mol). Melanotan I is a peptide; Pal-GHK is a lipopeptide. These formulas refer to the parent compounds without salt counter-ions.

A 5 mg vial of Melanotan I equals how many mg of Pal-GHK in moles?

5 mg of Melanotan I (MW 1646.8) is 3.036 µmol. The same amount of Pal-GHK (MW 578.8) would weigh 1.757 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 10 mg vial of Melanotan I equals how many mg of Pal-GHK in moles?

10 mg of Melanotan I (MW 1646.8) is 6.072 µmol. The same amount of Pal-GHK (MW 578.8) would weigh 3.515 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

A 10 mg vial of Pal-GHK equals how many mg of Melanotan I in moles?

10 mg of Pal-GHK (MW 578.8) is 17.277 µmol. The same amount of Melanotan I (MW 1646.8) would weigh 28.452 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.

More questions about melanotan-i

A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.

Cite this

Research use only. Not for consumption. No health claims.

Plain

Sable Peptides. (2026). What is the difference between Melanotan I and Pal-GHK?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/melanotan-i-vs-pal-ghk/#sqa-040144

APA

Sable Peptides. (2026, October 11). *What is the difference between Melanotan I and Pal-GHK?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/melanotan-i-vs-pal-ghk/#sqa-040144

BibTeX

@misc{sable_#sqa-040144_2026,
  author = {{Sable Peptides}},
  title = {{What is the difference between Melanotan I and Pal-GHK?}},
  year = {2026},
  howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/melanotan-i-vs-pal-ghk/#sqa-040144}},
  note = {Accessed 11 October 2026. CC BY 4.0}
}

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Date modified: 2026-10-10