Sable · Question
What is the difference between Matrixyl and P21?
Matrixyl is a palmitoylated pentapeptide derived from a procollagen I fragment, widely studied in cosmetic-science and fibroblast-culture research (lipopeptide, MW about 802.1 g/mol).
Research use only. Not for human consumption. No health claims.
Last verified 2026-10-10
What is the difference between Matrixyl and P21?
Matrixyl is a palmitoylated pentapeptide derived from a procollagen I fragment, widely studied in cosmetic-science and fibroblast-culture research (lipopeptide, MW about 802.1 g/mol).
Which is heavier, Matrixyl or P21?
Matrixyl has a molecular weight of about 802.1 g/mol and P21 about 578.7 g/mol (PubChem), so Matrixyl is heavier by 223.4 g/mol, a ratio of 1.39. This means 1 mg of Matrixyl contains 1,246.7 nmol versus 1,728 nmol for P21.
How many mg of P21 are equimolar to 1 mg of Matrixyl?
1 mg of Matrixyl (MW 802.1) is 1,246.7 nmol. The same number of moles of P21 (MW 578.7) weighs 0.7215 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of Matrixyl and P21
PubChem lists Matrixyl as C39H75N7O10 (802.1 g/mol) and P21 as C27H42N6O8 (578.7 g/mol). Matrixyl is a lipopeptide; P21 is a peptidomimetic. These formulas refer to the parent compounds without salt counter-ions.
A 5 mg vial of Matrixyl equals how many mg of P21 in moles?
5 mg of Matrixyl (MW 802.1) is 6.234 µmol. The same amount of P21 (MW 578.7) would weigh 3.607 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of Matrixyl equals how many mg of P21 in moles?
10 mg of Matrixyl (MW 802.1) is 12.467 µmol. The same amount of P21 (MW 578.7) would weigh 7.215 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of P21 equals how many mg of Matrixyl in moles?
10 mg of P21 (MW 578.7) is 17.28 µmol. The same amount of Matrixyl (MW 802.1) would weigh 13.86 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of P21 equals how many mg of Matrixyl in moles?
5 mg of P21 (MW 578.7) is 8.64 µmol. The same amount of Matrixyl (MW 802.1) would weigh 6.93 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between Matrixyl and P21?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/matrixyl-vs-p21/#sqa-041269
APA
Sable Peptides. (2026, October 11). *What is the difference between Matrixyl and P21?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/matrixyl-vs-p21/#sqa-041269
BibTeX
@misc{sable_#sqa-041269_2026,
author = {{Sable Peptides}},
title = {{What is the difference between Matrixyl and P21?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/matrixyl-vs-p21/#sqa-041269}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10