Sable · Question
What is the difference between MOTS-c and Matrixyl?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
Research use only. Not for human consumption. No health claims.
Last verified 2026-10-10
What is the difference between MOTS-c and Matrixyl?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded in the 12S rRNA region, described in 2015 and studied in cellular metabolism research (peptide, MW about 2174.6 g/mol).
Which is heavier, MOTS-c or Matrixyl?
MOTS-c has a molecular weight of about 2174.6 g/mol and Matrixyl about 802.1 g/mol (PubChem), so MOTS-c is heavier by 1,372.5 g/mol, a ratio of 2.71. This means 1 mg of MOTS-c contains 459.9 nmol versus 1,246.7 nmol for Matrixyl.
How many mg of Matrixyl are equimolar to 1 mg of MOTS-c?
1 mg of MOTS-c (MW 2174.6) is 459.9 nmol. The same number of moles of Matrixyl (MW 802.1) weighs 0.3688 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of MOTS-c and Matrixyl
PubChem lists MOTS-c as C101H152N28O22S2 (2174.6 g/mol) and Matrixyl as C39H75N7O10 (802.1 g/mol). MOTS-c is a peptide; Matrixyl is a lipopeptide. These formulas refer to the parent compounds without salt counter-ions.
A 5 mg vial of MOTS-c equals how many mg of Matrixyl in moles?
5 mg of MOTS-c (MW 2174.6) is 2.299 µmol. The same amount of Matrixyl (MW 802.1) would weigh 1.844 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of MOTS-c equals how many mg of Matrixyl in moles?
10 mg of MOTS-c (MW 2174.6) is 4.599 µmol. The same amount of Matrixyl (MW 802.1) would weigh 3.688 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of MOTS-c equals how many mg of Matrixyl in moles?
20 mg of MOTS-c (MW 2174.6) is 9.197 µmol. The same amount of Matrixyl (MW 802.1) would weigh 7.377 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 30 mg vial of MOTS-c equals how many mg of Matrixyl in moles?
30 mg of MOTS-c (MW 2174.6) is 13.796 µmol. The same amount of Matrixyl (MW 802.1) would weigh 11.065 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 40 mg vial of MOTS-c equals how many mg of Matrixyl in moles?
40 mg of MOTS-c (MW 2174.6) is 18.394 µmol. The same amount of Matrixyl (MW 802.1) would weigh 14.754 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of Matrixyl equals how many mg of MOTS-c in moles?
5 mg of Matrixyl (MW 802.1) is 6.234 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 13.556 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of Matrixyl equals how many mg of MOTS-c in moles?
10 mg of Matrixyl (MW 802.1) is 12.467 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 27.111 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between MOTS-c and Matrixyl?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/matrixyl-vs-mots-c/#sqa-040037
APA
Sable Peptides. (2026, October 11). *What is the difference between MOTS-c and Matrixyl?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/matrixyl-vs-mots-c/#sqa-040037
BibTeX
@misc{sable_#sqa-040037_2026,
author = {{Sable Peptides}},
title = {{What is the difference between MOTS-c and Matrixyl?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/matrixyl-vs-mots-c/#sqa-040037}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10