Sable · Question
What is the difference between LL-37 and MOTS-c?
LL-37 is the 37-residue active fragment of the human cathelicidin hCAP18, studied in antimicrobial-peptide and innate-immunity research (peptide, MW about 4493 g/mol).
Research use only. Not for human consumption. No health claims.
Last verified 2026-10-10
What is the difference between LL-37 and MOTS-c?
LL-37 is the 37-residue active fragment of the human cathelicidin hCAP18, studied in antimicrobial-peptide and innate-immunity research (peptide, MW about 4493 g/mol).
Which is heavier, LL-37 or MOTS-c?
LL-37 has a molecular weight of about 4493 g/mol and MOTS-c about 2174.6 g/mol (PubChem), so LL-37 is heavier by 2,318.4 g/mol, a ratio of 2.07. This means 1 mg of LL-37 contains 222.6 nmol versus 459.9 nmol for MOTS-c.
How many mg of MOTS-c are equimolar to 1 mg of LL-37?
1 mg of LL-37 (MW 4493) is 222.6 nmol. The same number of moles of MOTS-c (MW 2174.6) weighs 0.484 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of LL-37 and MOTS-c
PubChem lists LL-37 as C205H340N60O53 (4493 g/mol) and MOTS-c as C101H152N28O22S2 (2174.6 g/mol). LL-37 is a peptide; MOTS-c is a peptide. These formulas refer to the parent compounds without salt counter-ions.
A 10 mg vial of LL-37 equals how many mg of MOTS-c in moles?
10 mg of LL-37 (MW 4493) is 2.226 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 4.84 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of LL-37 equals how many mg of MOTS-c in moles?
5 mg of LL-37 (MW 4493) is 1.113 µmol. The same amount of MOTS-c (MW 2174.6) would weigh 2.42 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of MOTS-c equals how many mg of LL-37 in moles?
5 mg of MOTS-c (MW 2174.6) is 2.299 µmol. The same amount of LL-37 (MW 4493) would weigh 10.331 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of MOTS-c equals how many mg of LL-37 in moles?
10 mg of MOTS-c (MW 2174.6) is 4.599 µmol. The same amount of LL-37 (MW 4493) would weigh 20.661 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of MOTS-c equals how many mg of LL-37 in moles?
20 mg of MOTS-c (MW 2174.6) is 9.197 µmol. The same amount of LL-37 (MW 4493) would weigh 41.323 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 30 mg vial of MOTS-c equals how many mg of LL-37 in moles?
30 mg of MOTS-c (MW 2174.6) is 13.796 µmol. The same amount of LL-37 (MW 4493) would weigh 61.984 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 40 mg vial of MOTS-c equals how many mg of LL-37 in moles?
40 mg of MOTS-c (MW 2174.6) is 18.394 µmol. The same amount of LL-37 (MW 4493) would weigh 82.645 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between LL-37 and MOTS-c?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/ll-37-vs-mots-c/#sqa-039854
APA
Sable Peptides. (2026, October 11). *What is the difference between LL-37 and MOTS-c?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/ll-37-vs-mots-c/#sqa-039854
BibTeX
@misc{sable_#sqa-039854_2026,
author = {{Sable Peptides}},
title = {{What is the difference between LL-37 and MOTS-c?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/ll-37-vs-mots-c/#sqa-039854}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10