Sable · Question
What is the difference between LL-37 and Melanotan II?
LL-37 is the 37-residue active fragment of the human cathelicidin hCAP18, studied in antimicrobial-peptide and innate-immunity research (peptide, MW about 4493 g/mol).
Research use only. Not for human consumption. No health claims.
Last verified 2026-10-10
What is the difference between LL-37 and Melanotan II?
LL-37 is the 37-residue active fragment of the human cathelicidin hCAP18, studied in antimicrobial-peptide and innate-immunity research (peptide, MW about 4493 g/mol).
Which is heavier, LL-37 or Melanotan II?
LL-37 has a molecular weight of about 4493 g/mol and Melanotan II about 1024.2 g/mol (PubChem), so LL-37 is heavier by 3,468.8 g/mol, a ratio of 4.39. This means 1 mg of LL-37 contains 222.6 nmol versus 976.4 nmol for Melanotan II.
How many mg of Melanotan II are equimolar to 1 mg of LL-37?
1 mg of LL-37 (MW 4493) is 222.6 nmol. The same number of moles of Melanotan II (MW 1024.2) weighs 0.228 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of LL-37 and Melanotan II
PubChem lists LL-37 as C205H340N60O53 (4493 g/mol) and Melanotan II as C50H69N15O9 (1024.2 g/mol). LL-37 is a peptide; Melanotan II is a cyclic peptide. These formulas refer to the parent compounds without salt counter-ions.
A 10 mg vial of LL-37 equals how many mg of Melanotan II in moles?
10 mg of LL-37 (MW 4493) is 2.226 µmol. The same amount of Melanotan II (MW 1024.2) would weigh 2.28 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of LL-37 equals how many mg of Melanotan II in moles?
5 mg of LL-37 (MW 4493) is 1.113 µmol. The same amount of Melanotan II (MW 1024.2) would weigh 1.14 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between LL-37 and Melanotan II?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/ll-37-vs-melanotan-ii/#sqa-039862
APA
Sable Peptides. (2026, October 11). *What is the difference between LL-37 and Melanotan II?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/ll-37-vs-melanotan-ii/#sqa-039862
BibTeX
@misc{sable_#sqa-039862_2026,
author = {{Sable Peptides}},
title = {{What is the difference between LL-37 and Melanotan II?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/ll-37-vs-melanotan-ii/#sqa-039862}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10