Sable · Question
What is the difference between FOXO4-DRI and TB-500?
FOXO4-DRI is a D-retro-inverso peptide designed to interfere with FOXO4-p53 binding, described in a 2017 Cell paper on senescent-cell research in mice (peptide (D-retro-inverso), MW about 5358 g/mol).
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Last verified 2026-10-10
What is the difference between FOXO4-DRI and TB-500?
FOXO4-DRI is a D-retro-inverso peptide designed to interfere with FOXO4-p53 binding, described in a 2017 Cell paper on senescent-cell research in mice (peptide (D-retro-inverso), MW about 5358 g/mol).
Which is heavier, FOXO4-DRI or TB-500?
FOXO4-DRI has a molecular weight of about 5358 g/mol and TB-500 about 889 g/mol (PubChem), so FOXO4-DRI is heavier by 4,469 g/mol, a ratio of 6.03. This means 1 mg of FOXO4-DRI contains 186.6 nmol versus 1,124.9 nmol for TB-500.
How many mg of TB-500 are equimolar to 1 mg of FOXO4-DRI?
1 mg of FOXO4-DRI (MW 5358) is 186.6 nmol. The same number of moles of TB-500 (MW 889) weighs 0.1659 mg. Equimolar comparisons matter when testing two compounds side by side in the same assay.
Compare the molecular formulas of FOXO4-DRI and TB-500
PubChem lists FOXO4-DRI as C228H388N86O64 (5358 g/mol) and TB-500 as C38H68N10O14 (889 g/mol). FOXO4-DRI is a peptide (D-retro-inverso); TB-500 is a peptide. These formulas refer to the parent compounds without salt counter-ions.
A 5 mg vial of FOXO4-DRI equals how many mg of TB-500 in moles?
5 mg of FOXO4-DRI (MW 5358) is 0.9332 µmol. The same amount of TB-500 (MW 889) would weigh 0.8296 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of FOXO4-DRI equals how many mg of TB-500 in moles?
10 mg of FOXO4-DRI (MW 5358) is 1.866 µmol. The same amount of TB-500 (MW 889) would weigh 1.659 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 10 mg vial of TB-500 equals how many mg of FOXO4-DRI in moles?
10 mg of TB-500 (MW 889) is 11.249 µmol. The same amount of FOXO4-DRI (MW 5358) would weigh 60.27 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 2 mg vial of TB-500 equals how many mg of FOXO4-DRI in moles?
2 mg of TB-500 (MW 889) is 2.25 µmol. The same amount of FOXO4-DRI (MW 5358) would weigh 12.054 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 5 mg vial of TB-500 equals how many mg of FOXO4-DRI in moles?
5 mg of TB-500 (MW 889) is 5.624 µmol. The same amount of FOXO4-DRI (MW 5358) would weigh 30.135 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 15 mg vial of TB-500 equals how many mg of FOXO4-DRI in moles?
15 mg of TB-500 (MW 889) is 16.873 µmol. The same amount of FOXO4-DRI (MW 5358) would weigh 90.405 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
A 20 mg vial of TB-500 equals how many mg of FOXO4-DRI in moles?
20 mg of TB-500 (MW 889) is 22.497 µmol. The same amount of FOXO4-DRI (MW 5358) would weigh 120.5 mg. This equimolar conversion lets two compounds be compared at matched molar amounts in the same experiment.
More questions about foxo4-dri
A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.
Cite this
Research use only. Not for consumption. No health claims.
Plain
Sable Peptides. (2026). What is the difference between FOXO4-DRI and TB-500?. UK Research Peptide Reference. Retrieved 11 October 2026, from https://www.sablepeptides.co.uk/questions/compare/foxo4-dri-vs-tb-500/#sqa-038843
APA
Sable Peptides. (2026, October 11). *What is the difference between FOXO4-DRI and TB-500?*. UK Research Peptide Reference. https://www.sablepeptides.co.uk/questions/compare/foxo4-dri-vs-tb-500/#sqa-038843
BibTeX
@misc{sable_#sqa-038843_2026,
author = {{Sable Peptides}},
title = {{What is the difference between FOXO4-DRI and TB-500?}},
year = {2026},
howpublished = {\url{https://www.sablepeptides.co.uk/questions/compare/foxo4-dri-vs-tb-500/#sqa-038843}},
note = {Accessed 11 October 2026. CC BY 4.0}
}Badge
<a href="https://www.sablepeptides.co.uk/ref"><img src="https://www.sablepeptides.co.uk/badge/ref.svg" alt="Data: UK Research Peptide Reference — Sable Peptides" width="220" height="40"></a>
Date modified: 2026-10-10