What is the amino acid sequence of AOD 9604?
AOD 9604 is a research peptide whose amino acid sequence is on the public registry record. The published sequence is H-Tyr-Leu-Arg-Ile-Val-Gln-Cys(1)-Arg-Ser-Val-Glu-Gly-Ser-Cys(1)-Gly-Phe-OH (Cys7-Cys14 disulfide). Its molecular formula is C78H123N23O23S2. Its molecular weight is 1815.1 g/mol. The CAS Registry Number is 221231-10-3.
Sequence. H-Tyr-Leu-Arg-Ile-Val-Gln-Cys(1)-Arg-Ser-Val-Glu-Gly-Ser-Cys(1)-Gly-Phe-OH (Cys7-Cys14 disulfide)
Class. peptide.
Formula. C78H123N23O23S2.
Mass. 1815.1 g/mol.
Analytical note. Identity confirmation by mass spectrometry uses the mass calculated from the formula. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use.
Sources
- https://pubchem.ncbi.nlm.nih.gov/rest/pug_view/data/compound/71300630/JSON?heading=Biologic%20Line%20Notation
- https://pubchem.ncbi.nlm.nih.gov/compound/71300630
AOD 9604: reference facts
7 AOD 9604 values, each linked to its public source; see the AOD 9604 reference page.
| Synonyms | AOD-9604; hGH fragment 176-191 analogue (Tyr-modified) (pubchem.ncbi.nlm.nih.gov) |
|---|---|
| Compound class | peptide (pubchem.ncbi.nlm.nih.gov) |
| CAS Registry Number | 221231-10-3 (pubchem.ncbi.nlm.nih.gov) |
| Molecular formula | C78H123N23O23S2 (pubchem.ncbi.nlm.nih.gov) |
| Molecular weight | 1815.1 g/mol (pubchem.ncbi.nlm.nih.gov) |
| PubChem CID | 71300630 (pubchem.ncbi.nlm.nih.gov) |
| Storage (lyophilised) | -20 °C, dry, protected from light (sigmaaldrich.com) |
Calculated sequence properties
Computed from the listed sequence. See the methodology.
| Length | 16 residues |
|---|---|
| Theoretical pI | 9.35 (calculated from sequence) |
| Net charge at pH 7 | 0.98 (calculated) |
| Extinction coefficient, 280 nm | 1615 M⁻¹cm⁻¹ (calculated) |
| Structure note | Cys7-Cys14 disulfide |
Sizes and prices at Sable
| Vial | Price | Per mg | UK same-size check (2026-10-16) |
|---|---|---|---|
| 2 mg | £14.29 | £7.15 | lowest other £22.90 across 2 UK sellers |
| 5 mg | £14.93 | £2.99 | lowest other £14.95 across 7 UK sellers |
| 10 mg | £34.99 | £3.50 | lowest other £39.99 across 4 UK sellers |
Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: CoA library.
Typical analytical method
| HPLC column | C18 reversed-phase (100-120 A pore) |
|---|---|
| Mobile phase | A: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min) |
| Detection | 214-220 nm (peptide bond) and 280 nm (Trp/Tyr present) |
General literature method. The lot CoA records the method actually used. How to read an HPLC chromatogram.
Related questions
Lyophilised storage on file: AOD 9604
From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See peptide storage.
| Compound | Lyophilised storage | Light / notes |
|---|---|---|
| AOD 9604 | -20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeks | protect from light; contains Met/Cys/Trp: oxidation-prone; minimise air/headspace exposure (source) |
Typical analytical method: AOD 9604
Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See how to read a CoA.
| Compound | HPLC column / detection | MS / expected ion |
|---|---|---|
| AOD 9604 | C18 reversed-phase (100-120 A pore); 214-220 nm (peptide bond) and 280 nm (Trp/Tyr present) | ESI-MS (positive mode); LC-MS for identity; [M+1H]1+ ~1816.1; [M+2H]2+ ~908.6; [M+3H]3+ ~606.0 |
Research use only. Not a medicine. Not for human or veterinary use.