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Sable Peptides

Research References Library: Sources Behind Sable's Guides

Research References Library: Sources Behind Sable's Guides is supplied for laboratory research only. Key facts are below; stored as lyophilised powder.

Last verified 12 Oct 2026.

A CoA for every lot; each vial carries a printed lot number that matches it. Ask with the lot number and we send it.

The short answer

These are the verified primary sources behind Sable's method guides, grouped by topic. Compound-specific facts are cited on each /ref page.

Research use only. Sable Peptides supplies laboratory reagents for in vitro and laboratory research by qualified people. Not a medicine. Not for human or veterinary use.

The short answer

These are the verified primary sources behind Sable's method guides, grouped by topic. Compound-specific facts are cited on each /ref page.

By topic

- Synthesis: Merrifield 1963; Coin et al. 2007. - Purification and HPLC: Mant et al. 2007. - Mass spectrometry: Fenn et al. 1989; Aebersold & Mann 2003. - Stability and degradation: Manning et al. 1989 and 2010; Wang 1999; Geiger & Clarke 1987; Robinson & Robinson 2001; Li et al. 1995. - Freeze-drying: Tang & Pikal 2004; Kim et al. 1998. - Solubility: Kramer et al. 2012. - Counter-ions: Cornish et al. 1999. - Packaging: Iacocca et al. 2010. - Content analysis: Rutherfurd & Gilani 2009. - Structure: Pauling et al. 1951; Anfinsen 1973. - Signalling and peptide design: Rosenbaum et al. 2009; Muttenthaler et al. 2021.

The full citations with PubMed and DOI links are listed below.

- /ref - /learn - /learn/peptide-research-topics

Sources

1. Merrifield RB. Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide. *Journal of the American Chemical Society* 1963;85:2149-2154. doi:10.1021/ja00897a025 2. Coin I et al.. Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences. *Nat Protoc* 2007;2:3247-56. PMID 18079725. doi:10.1038/nprot.2007.454 3. Mant CT et al.. HPLC analysis and purification of peptides. *Methods Mol Biol* 2007;386:3-55. PMID 18604941. PMC7119934. doi:10.1007/978-1-59745-430-8_1 4. Fenn JB et al.. Electrospray ionization for mass spectrometry of large biomolecules. *Science* 1989;246:64-71. PMID 2675315. doi:10.1126/science.2675315 5. Aebersold R et al.. Mass spectrometry-based proteomics. *Nature* 2003;422:198-207. PMID 12634793. doi:10.1038/nature01511 6. Manning MC et al.. Stability of protein pharmaceuticals. *Pharm Res* 1989;6:903-18. PMID 2687836. doi:10.1023/a:1015929109894 7. Manning MC et al.. Stability of protein pharmaceuticals: an update. *Pharm Res* 2010;27:544-75. PMID 20143256. doi:10.1007/s11095-009-0045-6 8. Wang W. Instability, stabilization, and formulation of liquid protein pharmaceuticals. *Int J Pharm* 1999;185:129-88. PMID 10460913. doi:10.1016/s0378-5173(99)00152-000152-0) 9. Tang X et al.. Design of freeze-drying processes for pharmaceuticals: practical advice. *Pharm Res* 2004;21:191-200. PMID 15032301. doi:10.1023/b:pham.0000016234.73023.75 10. Kim AI et al.. The physical state of mannitol after freeze-drying: effects of mannitol concentration, freezing rate, and a noncrystallizing cosolute. *J Pharm Sci* 1998;87:931-5. PMID 9687336. doi:10.1021/js980001d 11. Geiger T et al.. Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation. *J Biol Chem* 1987;262:785-94. PMID 3805008. 12. Robinson NE et al.. Molecular clocks. *Proc Natl Acad Sci U S A* 2001;98:944-9. PMID 11158575. PMC14689. doi:10.1073/pnas.98.3.944 13. Li S et al.. Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization. *Biotechnol Bioeng* 1995;48:490-500. PMID 18623513. doi:10.1002/bit.260480511 14. Kramer RM et al.. Toward a molecular understanding of protein solubility: increased negative surface charge correlates with increased solubility. *Biophys J* 2012;102:1907-15. PMID 22768947. PMC3328702. doi:10.1016/j.bpj.2012.01.060 15. Cornish J et al.. Trifluoroacetate, a contaminant in purified proteins, inhibits proliferation of osteoblasts and chondrocytes. *Am J Physiol* 1999;277:E779-83. PMID 10567002. doi:10.1152/ajpendo.1999.277.5.E779 16. Iacocca RG et al.. Factors affecting the chemical durability of glass used in the pharmaceutical industry. *AAPS PharmSciTech* 2010;11:1340-9. PMID 20740334. PMC2974153. doi:10.1208/s12249-010-9506-9 17. Rutherfurd SM et al.. Amino acid analysis. *Curr Protoc Protein Sci* 2009;Chapter 11:11.9.1-11.9.37. PMID 19937719. doi:10.1002/0471140864.ps1109s58 18. Pauling L et al.. The structure of proteins; two hydrogen-bonded helical configurations of the polypeptide chain. *Proc Natl Acad Sci U S A* 1951;37:205-11. PMID 14816373. PMC1063337. doi:10.1073/pnas.37.4.205 19. Anfinsen CB. Principles that govern the folding of protein chains. *Science* 1973;181:223-30. PMID 4124164. doi:10.1126/science.181.4096.223 20. Rosenbaum DM et al.. The structure and function of G-protein-coupled receptors. *Nature* 2009;459:356-63. PMID 19458711. PMC3967846. doi:10.1038/nature08144 21. Muttenthaler M et al.. Trends in peptide drug discovery. *Nat Rev Drug Discov* 2021;20:309-325. PMID 33536635. doi:10.1038/s41573-020-00135-8 22. PubChem (compound identity data). 23. ICH quality guidelines.

*Last reviewed: 2026-10-10. Original Sable content; sources verified via PubMed E-utilities / Crossref / live HTTP checks on 2026-10-10.*

Last reviewed: 2026-10-10

How much does Research References Library: Sources Behind Sable's Guides cost in the UK?

Frequently asked questions

How were these references chosen?

They are primary papers and reviews on peptide chemistry, analysis and handling, each verified against PubMed or Crossref.

Where are compound-specific sources?

On each /ref/{slug} page, where every fact links to its source, usually PubChem.

Are these references about effects in people?

No. This library covers chemistry, analytical methods and laboratory handling only.

How often is it updated?

When a guide is added or revised; the page shows its last-reviewed date.

Can I suggest a reference?

Yes, through the site contact route. It will be verified before it is added.