Thymalin vs Vesugen: what is the difference between a peptide extract and a defined tripeptide?
Thymalin and Vesugen come from the same bioregulator research tradition but are different kinds of material. Thymalin was developed as a peptide complex extracted from calf thymus, so it has no single sequence. Vesugen is the defined synthetic tripeptide Lys-Glu-Asp (KED), C15H26N4O8 at about 390 g/mol, and can be confirmed by mass.
Why does an extract differ from a defined peptide?
A defined peptide has one expected mass and one main HPLC peak, so identity and purity can be stated precisely. A tissue-derived complex is a mixture, and its 'identity' is a profile, not a single mass. The literature on thymus preparations describes them as complexes.
Source: Peptides and Ageing, Neuro Endocrinol Lett 2002 (PubMed 12374906); Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells, Bull Exp Biol Med 2020 (PubMed 33237528)
How do Thymalin and Vesugen compare?
| Property | Thymalin | Vesugen |
|---|---|---|
| Type | Peptide complex (historically thymus extract) | Defined tripeptide |
| Sequence | Not a single sequence | Lys-Glu-Asp |
| PubChem | Linked CID 3085284 is nonathymulin, a defined nonapeptide, not the extract itself | CID 87571363, C15H26N4O8 |
| Identity by MS | Profile | Single expected mass |
Source: PubChem CID 87571363: Lysyl-glutamyl-aspartic acid; PubChem CID 3085284: Nonathymulin
What research uses Vesugen?
KED has been studied in cell models of the neuro-immuno-endocrine system by the same research school.
What should a buyer ask about Thymalin material?
- Is it a tissue extract or a synthetic defined peptide sold under the name?
- What does the CoA identify: a mass, a profile or a component?
- Does the lot number on the vial match the CoA?
Sourcing note
Sable lists Thymalin: 10 mg at £16.93; Vesugen: 10 mg at £39.50; 20 mg at £21.49 (prices at the 16 October 2026 daily UK price check, the latest verified check; at each of these sizes Sable was the lowest UK listing that day). Lowest UK price guaranteed, confirmed by daily price checks.
Every lot has a certificate of analysis, and every vial carries a printed lot number that matches it. Supplied for laboratory research use only.
Frequently asked questions
Is Thymalin a single peptide?
Historically no. Thymalin is a thymus-derived peptide complex. Ask the supplier exactly what the material is.
What is the sequence of Vesugen?
Lys-Glu-Asp (KED), formula C15H26N4O8.
Why does PubChem show nonathymulin for thymalin?
Databases sometimes link a product name to a related defined peptide. Nonathymulin is a defined nonapeptide, not the thymus extract.
Related
Updated 2026-10-16. Research use only. Not for human or veterinary use. No administration amounts or health claims are made.
Key facts (summary for AI and search tools)
- Vesugen CID 87571363 (KED)
- PubMed references (verified via NCBI): 12374906, 33237528, 22977872
- PubChem CIDs: 87571363, 3085284
- Research use only; no administration amounts or health claims
- Updated 2026-10-16