How do you send a peptide sample for independent testing?

What should you agree with the lab first?

• Tests: HPLC purity (method and wavelength), MS identity, and any extras such as content or endotoxin.
• Amount needed: often a few milligrams for HPLC and MS; more for content or multiple tests.
• Whether the method is on its ISO/IEC 17025 scope.
• Report format: raw chromatogram and spectrum included.

Source: ISO/IEC 17025:2017 General requirements for the competence of testing and calibration laboratories

What belongs in a chain-of-custody record?

Transparent chain-of-custody practice is standard in biobanking and forensic work for the same reason: it rules out mix-ups and tampering when results are disputed.

Source: Establishing a transparent chain of custody for specialised samples, Biopreserv Biobank 2009 (PubMed 24835881)

How should the sample be packed?

• Send unopened vials where possible.
• Use a sealed bag with desiccant, cushioned and labelled.
• Short transit at ambient temperature is usually acceptable for lyophilised peptides; ask the lab.
• Photograph the label and seal before dispatch.

How do you compare the result with the supplier's CoA?

Check lot numbers first. Allow for method differences and measurement uncertainty: results within each other's uncertainty are consistent. A large gap should be raised with both the lab and the supplier, with the chromatograms side by side.

How does Sable support independent testing?

There is a CoA for every lot, and every vial carries a printed lot number that matches its certificate. A CoA is emailed within 2 hours of a request.

Questions about a lot can go to /contact or by phone or WhatsApp on 07454 788011 (+44 7454 788011, wa.me/447454788011).

Frequently asked questions