Glossary

Piperidine

Piperidine is a cyclic secondary amine used, typically as a 20% solution in DMF, to remove the Fmoc protecting group during solid-phase peptide synthesis. It also traps the dibenzofulvene by-product. Its use is controlled in some jurisdictions, and alternatives such as 4-methylpiperidine are sometimes used.

Source: en.wikipedia.org

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