Glossary

Maleimide

Maleimide is a reactive group that forms stable thioether bonds with thiol groups, such as cysteine side chains, at near-neutral pH. Maleimide reagents are widely used for site-specific labelling and conjugation of cysteine-containing peptides. The resulting thiosuccinimide linkage can undergo slow exchange or hydrolysis.

Source: en.wikipedia.org

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