Glossary

Isoelectric point

The isoelectric point (pI) is the pH at which a molecule carries no net electrical charge. For a peptide, it depends on the ionisable N-terminus, C-terminus and side chains. Peptides are often least soluble near their pI, so choosing a buffer pH away from the pI can help dissolve a lyophilised peptide in the laboratory.

Source: en.wikipedia.org

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