---
title: "What is the amino acid sequence of triptorelin?"
description: "Triptorelin is a research peptide whose amino acid sequence is on the public registry record."
canonical: https://www.sablepeptides.co.uk/questions/triptorelin-sequence
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

# What is the amino acid sequence of triptorelin?

Triptorelin is a research peptide whose amino acid sequence is on the public registry record. The published sequence is pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2. Its molecular formula is C64H82N18O13. Its molecular weight is 1311.4 g/mol. The CAS Registry Number is 57773-63-4. PubChem CID 25074470 indexes the structure.

Sequence. pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2

Class. peptide.

Formula. C64H82N18O13.

Mass. 1311.4 g/mol.

Analytical note. Identity confirmation by mass spectrometry uses the mass calculated from the formula. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use.

## Sources

-   [https://pubchem.ncbi.nlm.nih.gov/compound/25074470](https://pubchem.ncbi.nlm.nih.gov/compound/25074470)

## Triptorelin: reference facts

8 Triptorelin values, each linked to its public source; see the [Triptorelin reference page](/ref/triptorelin).

| Synonyms | [D-Trp6]-LHRH (pubchem.ncbi.nlm.nih.gov) |
| --- | --- |
| Compound class | peptide (pubchem.ncbi.nlm.nih.gov) |
| CAS Registry Number | 57773-63-4 (pubchem.ncbi.nlm.nih.gov) |
| Sequence | pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 (pubchem.ncbi.nlm.nih.gov) |
| Molecular formula | C64H82N18O13 (pubchem.ncbi.nlm.nih.gov) |
| Molecular weight | 1311.4 g/mol (pubchem.ncbi.nlm.nih.gov) |
| PubChem CID | 25074470 (pubchem.ncbi.nlm.nih.gov) |
| Storage (lyophilised) | -20 °C, dry, protected from light (sigmaaldrich.com) |

## Calculated sequence properties

Computed from the listed sequence. See the [methodology](/data/methodology).

| Length | 10 residues |
| --- | --- |
| Theoretical pI | 11.3 (calculated from sequence) |
| Net charge at pH 7 | 1.24 (calculated) |
| Extinction coefficient, 280 nm | 12490 M⁻¹cm⁻¹ (calculated) |
| Structure note | N-terminal pyroglutamate (Glu side chain and N-terminus not ionisable; counted as E for composition only); 1 D-residue(s); same composition values as L-forms |

## Sizes and prices at Sable

| Vial | Price | Per mg | UK same-size check (2026-10-16) |
| --- | --- | --- | --- |
| 2 mg | £17.98 | £8.99 | no same-size match |
| 5 mg | £25.99 | £5.20 | no same-size match |

Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: [CoA library](/coa).

## Typical analytical method

| HPLC column | C18 reversed-phase (100-120 A pore) |
| --- | --- |
| Mobile phase | A: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min) |
| Detection | 214-220 nm (peptide bond) and 280 nm (Trp/Tyr present) |

General literature method. The lot CoA records the method actually used. [How to read an HPLC chromatogram](/learn/how-to-read-an-hplc-chromatogram).

## Related questions

-   [Is triptorelin a peptide?](/questions/is-triptorelin-a-peptide)

## Lyophilised storage on file: Triptorelin

From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See [peptide storage](/learn/peptide-storage-and-solubility).

| Compound | Lyophilised storage | Light / notes |
| --- | --- | --- |
| Triptorelin | -20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeks | protect from light; contains Met/Cys/Trp: oxidation-prone; minimise air/headspace exposure (source) |

## Typical analytical method: Triptorelin

Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See [how to read a CoA](/guides/how-to-read-a-coa).

| Compound | HPLC column / detection | MS / expected ion |
| --- | --- | --- |
| Triptorelin | C18 reversed-phase (100-120 A pore); 214-220 nm (peptide bond) and 280 nm (Trp/Tyr present) | ESI-MS (positive mode); LC-MS for identity; [M+1H]1+ ~1312.4; [M+2H]2+ ~656.7; [M+3H]3+ ~438.1 |

Research use only. Not a medicine. Not for human or veterinary use.