--- title: "What is the amino acid sequence of retatrutide?" description: "Retatrutide is a research peptide whose amino acid sequence is on the public registry record." canonical: https://www.sablepeptides.co.uk/questions/retatrutide-sequence publisher: Sable Peptides Limited (UK company 17488610) note: Research use only. Not for human or veterinary use. --- # What is the amino acid sequence of retatrutide? Retatrutide is a research peptide whose amino acid sequence is on the public registry record. The full published sequence is listed below; it includes non-standard residues and side-chain modifications as written in the source record. Its molecular formula is C221H342N46O68. Its molecular weight is 4731.3 g/mol. Sequence. H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-αMeLeu-Leu-Asp-Lys-Lys(N6-{2-\[2-(2-{\[N-(19-carboxynonadecanoyl)-L-γ-glutamyl\]amino}ethoxy)ethoxy\]acetyl})-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 (Lys side chain as named in WHO Proposed INN List 128, WHO Drug Information Vol. 36 No. 4, 2022, p. 1051) Class. peptide (lipidated). Formula. C221H342N46O68. Mass. 4731.3 g/mol. Analytical note. Identity confirmation by mass spectrometry uses the mass calculated from the formula. Sable's release specification is ≥99% by HPLC with identity confirmed against the expected mass (quality page). Research use only. Not a medicine. Not for human or veterinary use. ## Sources - [https://www.ebi.ac.uk/chembl/api/data/molecule/CHEMBL5095485.json](https://www.ebi.ac.uk/chembl/api/data/molecule/CHEMBL5095485.json) - [https://pubchem.ncbi.nlm.nih.gov/#query=retatrutide](https://pubchem.ncbi.nlm.nih.gov/#query=retatrutide) - [https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-(inn)/pl128.pdf](https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-\(inn\)/pl128.pdf) ## Retatrutide: reference facts 3 Retatrutide values, each linked to its public source; see the [Retatrutide reference page](/ref/retatrutide). | Synonyms | LY3437943 (pubchem.ncbi.nlm.nih.gov) | | --- | --- | | Compound class | peptide (lipidated) (pubchem.ncbi.nlm.nih.gov) | | Storage (lyophilised) | -20 °C, dry, protected from light (sigmaaldrich.com) | ## Sizes and prices at Sable | Vial | Price | Per mg | UK same-size check (2026-10-16) | | --- | --- | --- | --- | | 5 mg | £16.93 | £3.39 | lowest other £20.95 across 2 UK sellers | | 10 mg | £24.99 | £2.50 | lowest other £51.99 across 2 UK sellers | | 15 mg | £37.99 | £2.53 | lowest other £85.00 across 1 UK sellers | | 20 mg | £48.99 | £2.45 | lowest other £93.99 across 2 UK sellers | | 30 mg | £66.99 | £2.23 | lowest other £85.00 across 4 UK sellers | | 40 mg | £88.99 | £2.22 | no same-size match | | 50 mg | £108.99 | £2.18 | no same-size match | | 60 mg | £128.99 | £2.15 | no same-size match | Multi-vial pricing on the same item: 3+ vials 10% off, 5+ vials 15% off, 10+ vials 20% off. Every lot has a certificate of analysis: [CoA library](/coa). ## Typical analytical method | HPLC column | C18 reversed-phase (300 A pore, C4/C8 suitable for large/lipidated) | | --- | --- | | Mobile phase | A: water + 0.1% TFA; B: acetonitrile + 0.1% TFA; linear gradient (e.g. 5-65% B over 20-30 min) | | Detection | 214-220 nm (peptide bond) and 280 nm (Trp/Tyr present) | General literature method. The lot CoA records the method actually used. [How to read an HPLC chromatogram](/learn/how-to-read-an-hplc-chromatogram). ## Related questions - [What is the molecular formula of retatrutide?](/questions/retatrutide-molecular-formula) - [What is the molecular weight of retatrutide?](/questions/retatrutide-molecular-weight) - [What does Retatrutide dissolve in?](/questions/retatrutide-solubility) - [How stable is lyophilised Retatrutide?](/questions/retatrutide-stability-lyophilised) ## Lyophilised storage on file: Retatrutide From the Sable storage reference (lyophilised material only; temperature, light, moisture). Literature basis is linked per row. See [peptide storage](/learn/peptide-storage-and-solubility). | Compound | Lyophilised storage | Light / notes | | --- | --- | --- | | Retatrutide | -20 C long term (-80 C acceptable), sealed and desiccated; 2-8 C for weeks | protect from light; no specific sequence liabilities identified from sequence data on file (source) | ## Typical analytical method: Retatrutide Reference HPLC and MS conditions from the Sable analytical-methods file; a lot's CoA states the method actually used. See [how to read a CoA](/guides/how-to-read-a-coa). | Compound | HPLC column / detection | MS / expected ion | | --- | --- | --- | | Retatrutide | C18 reversed-phase (300 A pore, C4/C8 suitable for large/lipidated); 214-220 nm (peptide bond) and 280 nm (Trp/Tyr present) | ESI-MS (positive mode); LC-MS for identity; [M+3H]3+ ~1578.1; [M+4H]4+ ~1183.8; [M+5H]5+ ~947.3; [M+6H]6+ ~789.6 | Research use only. Not a medicine. Not for human or veterinary use.