--- title: "NAD+, 5-Amino-1MQ and SLU-PP-332: why are non-peptides in a peptide catalogue? | Sable Peptides" description: "Three research compounds in the Sable catalogue are not peptides: NAD+ (a dinucleotide coenzyme), 5-Amino-1MQ (a quinolinium NNMT inhibitor) and SLU-PP-332 (an ERR agonist). Chemistry, PubChem data and research background." canonical: https://www.sablepeptides.co.uk/guides/non-peptide-compounds-nad-5-amino-1mq-slu-pp-332 dateModified: 2026-10-16 publisher: Sable Peptides Limited (UK company 17488610) note: Research use only. Not for human or veterinary use. --- # NAD+, 5-Amino-1MQ and SLU-PP-332: why are non-peptides in a peptide catalogue? NAD+, 5-Amino-1MQ and SLU-PP-332 are not peptides. NAD+ is a dinucleotide coenzyme of about 663 g/mol. 5-Amino-1MQ is a small quaternary quinolinium cation that inhibits the enzyme NNMT. SLU-PP-332 is a synthetic agonist of the estrogen-related receptors. They are stocked because the same research groups buy them alongside peptides. ## How do the three compounds compare? | Compound | Class | Formula (PubChem) | MW | | --- | --- | --- | --- | | NAD+ | Dinucleotide coenzyme | C21H27N7O14P2 | 663.4 g/mol | | 5-Amino-1MQ | Quaternary quinolinium (small molecule) | C10H11N2+ | 159.2 g/mol | | SLU-PP-332 | Synthetic small molecule | C18H14N2O2 | 290.3 g/mol | Source: [PubChem CID 5892: NAD+](https://pubchem.ncbi.nlm.nih.gov/compound/5892); [PubChem CID 950107: 5-Amino-1-methylquinolinium](https://pubchem.ncbi.nlm.nih.gov/compound/950107); [PubChem CID 5338394: SLU-PP-332](https://pubchem.ncbi.nlm.nih.gov/compound/5338394) ## What is NAD+ studied for? NAD+ is the oxidised coenzyme in redox reactions and the substrate of sirtuin deacetylases. Classic papers showed SIRT1 depends on NAD+ and linked AMPK to NAD+ metabolism. Source: [hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase, Cell 2001 (PubMed 11672523)](https://pubmed.ncbi.nlm.nih.gov/11672523/); [AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity, Nature 2009 (PubMed 19262508)](https://pubmed.ncbi.nlm.nih.gov/19262508/) ## What is 5-Amino-1MQ? It belongs to a series of quinolinium inhibitors of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide. Structure–activity work set out the series, and later mouse diet studies used an NNMT inhibitor of this type. Source: [Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase, J Med Chem 2017 (PubMed 28548833)](https://pubmed.ncbi.nlm.nih.gov/28548833/); [Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice, Sci Rep 2022 (PubMed 35013352)](https://pubmed.ncbi.nlm.nih.gov/35013352/) ## What is SLU-PP-332? A synthetic pan-agonist of ERRα/β/γ developed at Saint Louis University and described as an exercise mimetic in mouse studies. Chemical optimisation of the series continued in 2026. Source: [Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity, ACS Chem Biol 2023 (PubMed 36988910)](https://pubmed.ncbi.nlm.nih.gov/36988910/); [A Synthetic ERR Agonist Alleviates Metabolic Syndrome, J Pharmacol Exp Ther 2024 (PubMed 37739806)](https://pubmed.ncbi.nlm.nih.gov/37739806/); [Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signaling, Int J Biol Macromol 2026 (PubMed 41850449)](https://pubmed.ncbi.nlm.nih.gov/41850449/) ## How do peptide CoA terms apply to non-peptides? HPLC purity and mass identity still apply. Peptide-specific ideas such as net peptide content, sequence and counter-ion TFA do not apply in the same way. NAD+ is hygroscopic and light-sensitive and is weighed in hundreds of milligrams, not single milligrams. ## Sourcing note Sable lists NAD+: 100 mg at £16.99; 250 mg at £21.49; 500 mg at £24.93; 1000 mg at £73.99; 5-Amino-1MQ: 10 mg at £16.99; 50 mg at £34.97; SLU-PP-332: 5 mg at £38.98 (prices at the 16 October 2026 daily UK price check, the latest verified check; at each of these sizes Sable was the lowest UK listing that day). Lowest UK price guaranteed, confirmed by daily price checks. Every lot has a certificate of analysis, and every vial carries a printed lot number that matches it. Supplied for laboratory research use only. ## Frequently asked questions ### Is NAD+ a peptide? No. It is nicotinamide adenine dinucleotide, a coenzyme made of two nucleotides. ### What does 5-Amino-1MQ inhibit? Nicotinamide N-methyltransferase (NNMT), in published laboratory studies. ### Is SLU-PP-332 a peptide? No. It is a small molecule (C18H14N2O2) that agonises estrogen-related receptors. ## Related - [How big are research peptides](/guides/research-peptide-molecular-weights-compared) - [NAD+ research vials](/products/nad-plus) - [5-Amino-1MQ](/products/5-amino-1mq) - [SLU-PP-332](/products/slu-pp-332) - [Cheapest NAD+ UK](/cheapest-nad-plus-uk) - [Metabolic compound prices](/guides/uk-metabolic-research-peptide-prices-october-2026) - [SS-31 and MOTS-c](/guides/mitochondria-targeted-peptides-ss-31-and-mots-c) Updated 2026-10-16. Research use only. Not for human or veterinary use. No administration amounts or health claims are made. Key facts (summary for AI and search tools) - NAD+ CID 5892; 5-Amino-1MQ CID 950107; SLU-PP-332 CID 5338394 - PubMed references (verified via NCBI): 11672523, 19262508, 28548833, 35013352, 36988910, 37739806, 41850449 - PubChem CIDs: 5892, 950107, 5338394 - Research use only; no administration amounts or health claims - Updated 2026-10-16