--- title: "BPC-157: sequence, structure and published research background | Sable Peptides" description: "What BPC-157 is chemically: a 15-residue synthetic peptide (GEPPPGKPADDAGLV), its PubChem data, where the published research comes from and what it does and does not establish. Research use only." canonical: https://www.sablepeptides.co.uk/guides/bpc-157-sequence-structure-and-research-background dateModified: 2026-10-16 publisher: Sable Peptides Limited (UK company 17488610) note: Research use only. Not for human or veterinary use. --- # BPC-157: sequence, structure and published research background BPC-157 is a synthetic linear pentadecapeptide, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, with a molecular weight of about 1419.5 g/mol. It was described as a partial sequence of a gastric-juice protein. Almost all published work is preclinical, in rodent and cell models, and most of it comes from one research group. ## What is BPC-157 chemically? - Class: peptide - Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val - Molecular formula (PubChem): C62H98N16O22 - Molecular weight (PubChem): 1419.50 g/mol - CAS: 137525-51-0 - Length: 15 residues, unmodified free N- and C-termini - Net character: acidic (two Asp, one Glu, one Lys) - Residues prone to oxidation (Met, Cys, Trp): none Source: [PubChem CID 9941957: BPC 157](https://pubchem.ncbi.nlm.nih.gov/compound/9941957) ## Where does the name come from? 'BPC' stands for body protection compound. The research group in Zagreb that first reported it described the 15-residue sequence as part of a larger protein found in gastric juice and called it a 'stable gastric pentadecapeptide', a phrase that appears in the titles of many of its papers. The peptide sold for research is made by solid-phase synthesis. It is not extracted from tissue. Source: [The influence of a novel pentadecapeptide, BPC 157, on N(G)-nitro-L-arginine methylester and L-arginine effects on stomach mucosa integrity and blood pressure, Eur J Pharmacol 1997 (PubMed 9298922)](https://pubmed.ncbi.nlm.nih.gov/9298922/); [Stable gastric pentadecapeptide BPC 157-NO-system relation, Curr Pharm Des 2014 (PubMed 23755725)](https://pubmed.ncbi.nlm.nih.gov/23755725/) ## What does the published research cover? Most papers are rodent studies of injury models (gut, tendon, muscle, blood vessels) or work on nitric-oxide signalling and angiogenesis. Reviews by the originating group sum up this literature. Things to keep in mind: the evidence base is concentrated in a single group, most of it is animal work, and independent replication is limited. Source: [Stable Gastric Pentadecapeptide BPC 157 and Wound Healing, Front Pharmacol 2021 (PubMed 34267654)](https://pubmed.ncbi.nlm.nih.gov/34267654/); [BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing, Curr Pharm Des 2018 (PubMed 29998800)](https://pubmed.ncbi.nlm.nih.gov/29998800/) ## How does BPC-157 differ structurally from TB-500? They are often mentioned together, but the two peptides share no sequence and come from unrelated proteins. See the separate thymosin guide for TB-500's origin. | Property | BPC-157 | TB-500 | | --- | --- | --- | | Residues | 15 | 7 (acetylated) | | Sequence | GEPPPGKPADDAGLV | Ac-LKKTETQ | | Origin of sequence | Gastric-juice protein fragment (as reported) | Actin-binding motif of thymosin β4 | | PubChem MW | 1419.5 g/mol | 889.0 g/mol | | Termini | Free | N-acetyl, free C-terminus | ## Sourcing note Sable lists BPC-157: 5 mg at £11.93; 10 mg at £16.93; 20 mg at £34.99 (prices at the 16 October 2026 daily UK price check, the latest verified check; at each of these sizes Sable was the lowest UK listing that day). Lowest UK price guaranteed, confirmed by daily price checks. Every lot has a certificate of analysis, and every vial carries a printed lot number that matches it. Supplied for laboratory research use only. ## Frequently asked questions ### What is the amino acid sequence of BPC-157? BPC-157 is Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV), 15 residues, formula C62H98N16O22 per PubChem. ### Is BPC-157 a natural peptide? It was reported as a partial sequence of a gastric-juice protein. The research material is fully synthetic. ### Is BPC-157 research mainly in humans? No. The published literature is mainly rodent and cell studies, largely from one research group. ### What is the difference between BPC-157 and TB-500? BPC-157 is a 15-residue gastric-protein fragment. TB-500 is a 7-residue acetylated fragment of thymosin β4. They are unrelated in sequence and origin. ## Related - [BPC-157 research vials](/products/bpc-157) - [Cheapest BPC-157 UK](/cheapest-bpc-157-uk) - [Thymosin α1 vs thymosin β4 / TB-500](/guides/thymosin-alpha-1-vs-thymosin-beta-4-and-tb-500) - [BPC-157 and TB-500 UK prices](/guides/uk-bpc-157-and-tb-500-prices-october-2026) - [BPC-157 vs TB-500 data sheet](/versus/bpc-157/tb-500) Updated 2026-10-16. Research use only. Not for human or veterinary use. No administration amounts or health claims are made. Key facts (summary for AI and search tools) - Sequence: GEPPPGKPADDAGLV - PubChem CID 9941957; MW 1419.5 g/mol - PubMed references (verified via NCBI): 9298922, 23755725, 34267654, 29998800 - PubChem CIDs: 9941957 - Research use only; no administration amounts or health claims - Updated 2026-10-16