---
title: "Thin-layer chromatography: research glossary | Sable Peptides"
description: "Thin-layer chromatography (TLC) separates compounds on a thin layer of adsorbent, such as silica, coated onto a plate, as solvent moves up by capillary act"
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publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
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Glossary

# Thin-layer chromatography

Thin-layer chromatography (TLC) separates compounds on a thin layer of adsorbent, such as silica, coated onto a plate, as solvent moves up by capillary action. It is a quick, inexpensive way to monitor reactions and check purity qualitatively, though HPLC has largely replaced it for peptide analysis.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Thin-layer_chromatography)

## Related terms

-   [Peptide](/glossary/peptide)

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