---
title: "Tandem mass spectrometry: research glossary | Sable Peptides"
description: "Tandem mass spectrometry (MS/MS) involves selecting a precursor ion, fragmenting it and analysing the resulting fragments. For peptides, fragmentation alon"
canonical: https://www.sablepeptides.co.uk/glossary/tandem-mass-spectrometry
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Tandem mass spectrometry

Tandem mass spectrometry (MS/MS) involves selecting a precursor ion, fragmenting it and analysing the resulting fragments. For peptides, fragmentation along the backbone produces b and y ion series whose mass differences reveal the amino acid sequence, confirming identity and locating modifications.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Tandem_mass_spectrometry)

## Related terms

-   [Amino acid](/glossary/amino-acid)
-   [Sequence](/glossary/sequence)
-   [Mass spectrometry](/glossary/mass-spectrometry)

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