---
title: "Sublimation: research glossary | Sable Peptides"
description: "Sublimation is the direct transition of a substance from the solid to the gas phase without passing through the liquid phase. In freeze-drying, ice in the"
canonical: https://www.sablepeptides.co.uk/glossary/sublimation
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Sublimation

Sublimation is the direct transition of a substance from the solid to the gas phase without passing through the liquid phase. In freeze-drying, ice in the frozen sample sublimes under vacuum at low temperature, leaving behind the dried solute. The rate depends on chamber pressure, shelf temperature and the sample's physical structure.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Sublimation_\(phase_transition\))

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