---
title: "Solubility: research glossary | Sable Peptides"
description: "Solubility is the maximum amount of a substance that can dissolve in a given volume of solvent at a specified temperature. Peptide solubility depends on se"
canonical: https://www.sablepeptides.co.uk/glossary/solubility
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Solubility

Solubility is the maximum amount of a substance that can dissolve in a given volume of solvent at a specified temperature. Peptide solubility depends on sequence, charge, hydrophobicity and pH. A common practice is to test solubility with a small portion of material before dissolving the whole vial, starting with water and adjusting as needed.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Solubility)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Hydrophobicity](/glossary/hydrophobicity)
-   [Sequence](/glossary/sequence)

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