---
title: "Sodium chloride: research glossary | Sable Peptides"
description: "Sodium chloride (NaCl) is an ionic compound commonly used to adjust ionic strength and tonicity in buffers. A 0.9% solution is isotonic saline. In peptide"
canonical: https://www.sablepeptides.co.uk/glossary/sodium-chloride
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Sodium chloride

Sodium chloride (NaCl) is an ionic compound commonly used to adjust ionic strength and tonicity in buffers. A 0.9% solution is isotonic saline. In peptide work it can help or hinder solubility depending on sequence, and it is non-volatile, so it must be removed before mass spectrometry.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Sodium_chloride)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Sequence](/glossary/sequence)
-   [Solubility](/glossary/solubility)
-   [Mass spectrometry](/glossary/mass-spectrometry)
-   [Ionic strength](/glossary/ionic-strength)

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