---
title: "Protease: research glossary | Sable Peptides"
description: "A protease is an enzyme that catalyses the hydrolysis of peptide bonds. Proteases differ in specificity: trypsin cleaves after lysine and arginine, while c"
canonical: https://www.sablepeptides.co.uk/glossary/protease
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Protease

A protease is an enzyme that catalyses the hydrolysis of peptide bonds. Proteases differ in specificity: trypsin cleaves after lysine and arginine, while chymotrypsin prefers aromatic residues. They degrade peptides in biological samples, and protease inhibitors or modified sequences are used to improve stability in experiments.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Protease)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Hydrolysis](/glossary/hydrolysis)
-   [Trypsin](/glossary/trypsin)
-   [Lysine](/glossary/lysine)
-   [Arginine](/glossary/arginine)

[Back to glossary A–Z](/glossary/terms)

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