---
title: "Proline: research glossary | Sable Peptides"
description: "Proline (three-letter code Pro, one-letter code P) is an amino acid whose side chain forms a ring with its backbone nitrogen, making it a secondary amine."
canonical: https://www.sablepeptides.co.uk/glossary/proline
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Proline

Proline (three-letter code Pro, one-letter code P) is an amino acid whose side chain forms a ring with its backbone nitrogen, making it a secondary amine. Proline restricts backbone flexibility, disrupts helices and sheets, and is common in turns. Peptide bonds before proline can adopt cis and trans forms.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Proline)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Amino acid](/glossary/amino-acid)
-   [One-letter code](/glossary/one-letter-code)

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