---
title: "Oxyma: research glossary | Sable Peptides"
description: "Oxyma, or ethyl cyanohydroxyiminoacetate, is a coupling additive used with carbodiimides such as DIC in peptide synthesis. It offers efficiency and racemis"
canonical: https://www.sablepeptides.co.uk/glossary/oxyma
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Oxyma

Oxyma, or ethyl cyanohydroxyiminoacetate, is a coupling additive used with carbodiimides such as DIC in peptide synthesis. It offers efficiency and racemisation suppression comparable to HOBt and HOAt while being considerably less hazardous, and is widely used in modern Fmoc solid-phase protocols.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Ethyl_cyanohydroxyiminoacetate)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Racemisation](/glossary/racemisation)

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