---
title: "N-terminus: research glossary | Sable Peptides"
description: "The N-terminus is the end of a peptide or protein chain that carries a free amino group. By convention, peptide sequences are written and numbered starting"
canonical: https://www.sablepeptides.co.uk/glossary/n-terminus
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# N-terminus

The N-terminus is the end of a peptide or protein chain that carries a free amino group. By convention, peptide sequences are written and numbered starting from the N-terminus. It is a common site for chemical modification, such as acetylation or attachment of labels, which can change charge, stability and the mass observed by mass spectrometry.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/N-terminus)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Acetylation](/glossary/acetylation)
-   [Mass spectrometry](/glossary/mass-spectrometry)

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