---
title: "Low-binding tube: research glossary | Sable Peptides"
description: "A low-binding tube is a plastic microcentrifuge tube with a surface modified or formulated to reduce adsorption of peptides and proteins. Dilute or hydroph"
canonical: https://www.sablepeptides.co.uk/glossary/low-binding-tube
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Low-binding tube

A low-binding tube is a plastic microcentrifuge tube with a surface modified or formulated to reduce adsorption of peptides and proteins. Dilute or hydrophobic peptides can be lost to the walls of standard polypropylene, causing apparent concentration to fall. Low-binding plastics and carrier proteins help maintain accurate concentrations in working solutions.

Source: [pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC10246705/)

## Related terms

-   [Adsorption](/glossary/adsorption)

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