---
title: "LC-MS: research glossary | Sable Peptides"
description: "Liquid chromatography-mass spectrometry (LC-MS) combines the separation power of HPLC with the mass identification of mass spectrometry. Each chromatograph"
canonical: https://www.sablepeptides.co.uk/glossary/lc-ms
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# LC-MS

Liquid chromatography-mass spectrometry (LC-MS) combines the separation power of HPLC with the mass identification of mass spectrometry. Each chromatographic peak can be assigned a mass, so impurities in a peptide sample can be characterised. Volatile mobile-phase additives such as formic acid are preferred for compatibility.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Liquid_chromatography%E2%80%93mass_spectrometry)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Formic acid](/glossary/formic-acid)
-   [Mass spectrometry](/glossary/mass-spectrometry)

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All Sable Peptides products are supplied for laboratory research use only. Not for consumption.