---
title: "Ionic strength: research glossary | Sable Peptides"
description: "Ionic strength is a measure of the total concentration of ions in a solution, weighted by the square of their charges. It influences electrostatic interact"
canonical: https://www.sablepeptides.co.uk/glossary/ionic-strength
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Ionic strength

Ionic strength is a measure of the total concentration of ions in a solution, weighted by the square of their charges. It influences electrostatic interactions, peptide solubility and aggregation, and retention in ion-exchange chromatography. Changing salt concentration is a common way to adjust ionic strength.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Ionic_strength)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Solubility](/glossary/solubility)
-   [Ion-exchange chromatography](/glossary/ion-exchange-chromatography)

[Back to glossary A–Z](/glossary/terms)

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