---
title: "IC50: research glossary | Sable Peptides"
description: "The IC50, or half maximal inhibitory concentration, is the concentration of a substance required to inhibit a biological or biochemical process by 50% in v"
canonical: https://www.sablepeptides.co.uk/glossary/ic50
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# IC50

The IC50, or half maximal inhibitory concentration, is the concentration of a substance required to inhibit a biological or biochemical process by 50% in vitro. It is used to compare the potency of inhibitors, including peptide-based and small-molecule enzyme inhibitors. IC50 values depend on assay conditions.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/IC50)

## Related terms

-   [Peptide](/glossary/peptide)
-   [In vitro](/glossary/in-vitro)

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