---
title: "G protein-coupled receptor: research glossary | Sable Peptides"
description: "G protein-coupled receptors (GPCRs) are a large family of cell-surface proteins with seven transmembrane helices that transmit signals by activating intrac"
canonical: https://www.sablepeptides.co.uk/glossary/g-protein-coupled-receptor
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# G protein-coupled receptor

G protein-coupled receptors (GPCRs) are a large family of cell-surface proteins with seven transmembrane helices that transmit signals by activating intracellular G proteins. Many peptide hormones and neuropeptides act through GPCRs, which are studied using binding and functional assays such as cAMP or calcium measurements.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/G_protein-coupled_receptor)

## Related terms

-   [Peptide](/glossary/peptide)

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