---
title: "Electrospray ionisation: research glossary | Sable Peptides"
description: "Electrospray ionisation (ESI) is a soft ionisation technique in which a liquid is sprayed through a charged capillary, producing fine droplets that evapora"
canonical: https://www.sablepeptides.co.uk/glossary/electrospray-ionisation
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Electrospray ionisation

Electrospray ionisation (ESI) is a soft ionisation technique in which a liquid is sprayed through a charged capillary, producing fine droplets that evaporate to release gas-phase ions. ESI generates multiply charged peptide ions with little fragmentation and couples directly to liquid chromatography in LC-MS.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Electrospray_ionization)

## Related terms

-   [Peptide](/glossary/peptide)
-   [LC-MS](/glossary/lc-ms)

[Back to glossary A–Z](/glossary/terms)

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