---
title: "Dissociation constant: research glossary | Sable Peptides"
description: "The dissociation constant (Kd) quantifies the affinity between a ligand and its binding partner, equal to the ligand concentration at which half the bindin"
canonical: https://www.sablepeptides.co.uk/glossary/dissociation-constant
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Dissociation constant

The dissociation constant (Kd) quantifies the affinity between a ligand and its binding partner, equal to the ligand concentration at which half the binding sites are occupied at equilibrium. Lower Kd values indicate tighter binding. Peptide-receptor interactions are often characterised by Kd values in the nanomolar range.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Dissociation_constant)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Nanomolar](/glossary/nanomolar)
-   [Receptor](/glossary/receptor)
-   [Ligand](/glossary/ligand)

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