---
title: "Diethyl ether: research glossary | Sable Peptides"
description: "Diethyl ether is a volatile, highly flammable organic solvent. In peptide synthesis, cold diethyl ether or methyl tert-butyl ether is used to precipitate c"
canonical: https://www.sablepeptides.co.uk/glossary/diethyl-ether
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Diethyl ether

Diethyl ether is a volatile, highly flammable organic solvent. In peptide synthesis, cold diethyl ether or methyl tert-butyl ether is used to precipitate crude peptide from the trifluoroacetic acid cleavage mixture, washing away scavengers and protecting-group by-products. It readily forms explosive peroxides on storage.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Diethyl_ether)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Cleavage](/glossary/cleavage)
-   [Trifluoroacetic acid](/glossary/trifluoroacetic-acid)
-   [Crude peptide](/glossary/crude-peptide)

[Back to glossary A–Z](/glossary/terms)

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