---
title: "Dichloromethane: research glossary | Sable Peptides"
description: "Dichloromethane (DCM) is a volatile chlorinated solvent used in peptide chemistry for resin swelling, washing and some coupling and cleavage procedures, pa"
canonical: https://www.sablepeptides.co.uk/glossary/dichloromethane
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Dichloromethane

Dichloromethane (DCM) is a volatile chlorinated solvent used in peptide chemistry for resin swelling, washing and some coupling and cleavage procedures, particularly with acid-sensitive resins. It must be handled in a fume hood because of its volatility and health hazards.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Dichloromethane)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Resin](/glossary/resin)
-   [Cleavage](/glossary/cleavage)
-   [Fume hood](/glossary/fume-hood)

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