---
title: "Deletion sequence: research glossary | Sable Peptides"
description: "A deletion sequence is a synthetic peptide impurity lacking one or more amino acids from the intended sequence, typically caused by incomplete coupling or"
canonical: https://www.sablepeptides.co.uk/glossary/deletion-sequence
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Deletion sequence

A deletion sequence is a synthetic peptide impurity lacking one or more amino acids from the intended sequence, typically caused by incomplete coupling or deprotection during solid-phase synthesis. Deletion peptides often elute close to the target on HPLC and are identified by mass spectrometry as species lighter than the target by the residue mass of the missing amino acid.

Source: [ema.europa.eu](https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-development-manufacture-synthetic-peptides_en.pdf)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Amino acid](/glossary/amino-acid)
-   [Residue](/glossary/residue)
-   [Sequence](/glossary/sequence)
-   [Mass spectrometry](/glossary/mass-spectrometry)

[Back to glossary A–Z](/glossary/terms)

All Sable Peptides products are supplied for laboratory research use only. Not for consumption.