---
title: "Crude peptide: research glossary | Sable Peptides"
description: "Crude peptide is the unpurified product obtained after cleavage from the synthesis resin and precipitation, typically in cold diethyl ether. It contains th"
canonical: https://www.sablepeptides.co.uk/glossary/crude-peptide
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Crude peptide

Crude peptide is the unpurified product obtained after cleavage from the synthesis resin and precipitation, typically in cold diethyl ether. It contains the target peptide along with deletion sequences, truncated chains, protecting-group adducts and scavenger residues. Purification by preparative HPLC is required to reach high purity.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Peptide_synthesis)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Resin](/glossary/resin)
-   [Cleavage](/glossary/cleavage)
-   [Scavenger](/glossary/scavenger)
-   [Preparative HPLC](/glossary/preparative-hplc)
-   [Precipitation](/glossary/precipitation)
-   [Diethyl ether](/glossary/diethyl-ether)

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